Study of MRI imaging with upper body raised for diagnosis of cerebrospinal fluid hypovolemia 2nd

Study of MRI imaging with upper body raised for diagnosis of cerebrospinal fluid hypovolemia 2nd - MURC study 2nd

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056367

Enrollment

Registered

2024-12-05

Start date

2025-02-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrospinal fluid hypovolemia

Interventions

Consent will be obtained from patients suspected of cerebrospinal fluid (CSF) hypovolemia who are likely to undergo lumbar puncture as part of their routine examination. Lumbar puncture for CSF pressu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with orthostatic headaches suspected of having cerebrospinal fluid (CSF) hypovolemia 2. Age 18 years or older 3. Patients undergoing cerebrospinal fluid pressure measurement via lumbar puncture

Exclusion criteria

Exclusion criteria: 1. Patients for whom MRI imaging is not feasible.

Design outcomes

Primary

Measure	Time frame
Quantitative evaluation of MRI image changes induced by postural adjustments and their correlation with cerebrospinal fluid pressure.	—

Secondary

Measure	Time frame
1. Measurement of the anteroposterior diameter of the dural sac in the lumbosacral region using whole-spine MRI 2. Measurement of signal intensity changes in the lumbosacral region due to postural adjustments 3. Measurement of the angle of the dural sac apex at the terminal end of the lumbosacral dural sac	—

Countries

Japan

Contacts

Public ContactEiichi Nakai

Kochi Medical School, Kochi University Neurosurgery

enakai@kochi-u.ac.jp0888802397

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026