Repeated implantation failure (RIF) with no previous pregnancies after two or more embryo transfers
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: No previous pregnancies History of two or more failed ART cycles
Exclusion criteria
Exclusion criteria: Azoospermia Known chromosomal abnormalities Significant uterine abnormalities (fibroids or adenomyosis >5cm) Endometrial thickness <7mm on the day of ET Cases with only cleavage-stage embryos Cases with PGT-A embryos
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate (proportion of cases with blood hCG levels >100 mIU/mL confirmed four weeks after embryo transfer) | — |
Secondary
| Measure | Time frame |
|---|---|
| Ongoing pregnancy rate (proportion of cases with confirmed gestational sac and fetal heart beats by trans-vaginal ultrasound analysis after nine weeks of gestation) | — |
Countries
Japan
Contacts
HORAC Grand Front Osaka Clinic Gynecology