Effects of Vitamin D 3 supplement on the cognitive status in patient with Systemic lupus Erythematosus with neuropsychiatric phenomenon.

Effects of Vitamin D 3 supplement on the cognitive status in patient with Systemic lupus Erythematosus with neuropsychiatric phenomenon. - Effects of Vitamin D 3 supplement on the cognitive status in patient with Systemic lupus Erythematosus with neuropsychiatric phenomenon. NPSLE Brain SPECT Vit D

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056299

Enrollment

Registered

2024-11-28

Start date

2021-02-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

While Vitamin D insufficiency is found to be associated with cognitive impairment in adults, the SLE itself is found to be associated with cognitive dysfunction (NPSLE) in about 39% [Semin Arthritis Rheum 2018

Interventions

vitamin D supplementation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Confirmed diagnosed cases of NPSLE (according to American College of Rheumatology Guideline) along with low vitamin D status.

Exclusion criteria

Exclusion criteria: Exclusion Criteria Current use of vitamin D3 or calcium supplement. Current or past diagnosis of cognitive impairment or dementia due to known brain disorders Use of certain drugs such as corticosteroid, hormone replacement, psychoactive drugs

Design outcomes

Primary

Measure	Time frame
Vitamin D3 supplementation led to substantial improvements in serum vitamin D levels, cognitive function (MMSE scores), and brain perfusion in the intervention group.	—

Countries

Asia(except Japan)

Contacts

Public ContactNasreen Sultana

National Institute of Nuclear Medicine & Allied Sciences(NINMAS) Dhaka

nasreeninm@yahoo.com+8801711481442

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026