Gynecologic Malignancies
Conditions
Interventions
None listed
Sponsors
Keio University School of Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: If the following criteria are met, the attending physician will confirm eligibility on the case registration form and proceed with enrollment: Diagnosis of a gynecologic malignancy cervical cancer, endometrial cancer, or ovarian cancer. Radical surgery has been performed. Six cycles of TC or TCBEV therapy are planned as postoperative adjuvant chemotherapy. Aged 20 years or older and under 80 years. Performance Status 0 - 2. Major organ functions are preserved. Patient is willing to undergo anticancer therapy combined with scalp cooling therapy. Written informed consent for participation in the study has been obtained from the patient.
Exclusion criteria
Exclusion criteria: (1) Skin diseases on the scalp (2) Alopecia (especially male-generated alopecia) (3) History of treatment with head radiation therapy (4)Allergy to Paclitaxel or Carboplatin (5) Allergy to silicone (6) Pregnant, lactating, may be pregnant, or intend to become pregnant (7) Ischemic heart disease (angina pectoris or myocardial infarction), concomitant cardiomyopathy, or history of cardiomyopathy (8) Has an active infection (9) Interstitial pneumonia or pulmonary fibrosis (10) Poorly controlled diabetes mellitus (HbA1c(NGSP) > 10.0%) (11) Concurrent overlapping cancers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of hair loss prevention after six courses of TC or TCBEV therapy combined with scalp cooling therapy following radical surgery in patients with gynecologic malignancies. | — |
Countries
Japan
Contacts
Public ContactSHINYA OKI
Keio University School of Medicine Department of Obstetrics and Gynecology
Outcome results
None listed