How intraoperative Electroencephalogram changes with different sedatives used during general anesthesia.

How intraoperative Electroencephalogram changes with different sedatives used during general anesthesia. - Effects of sedative drugs on the EEG.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056294

Enrollment

Registered

2024-11-28

Start date

2023-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia

Interventions

Anesthesia will be started with sevoflurane, and the sedation method will be switched to propofol intraoperatively. An EEG will be recorded for 20 minutes during each sedation. EEG recordings after th

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are at least 18 years of age and scheduled to undergo scheduled surgery, with a scheduled surgery time of at least 5 hours.

Exclusion criteria

Exclusion criteria: Patients with an American Society of Anesthesiologists physical status (ASA-PS) score of 3 or higher Emergency surgery Patients with preoperative cognitive dysfunction Patients taking antipsychotic medications Patients with drug or alcohol dependence Patients with a history of cerebral infarction, cerebral hemorrhage, or neurosurgery Patients who cannot have an EEG monitor placed on the forehead due to trauma or skin disorders

Design outcomes

Primary

Measure	Time frame
Differences in Alpha wave power in intraoperative EEG with propofol and sevoflurane	—

Countries

Japan

Contacts

Public Contacthideki iwata

kochi medical school department of anesthesiology and intensive care medicine

iwata_hideki@kochi-u.ac.jp088-880-2471

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026