The effect of the test diet on the absorption and excretion of water and electrolytes in the body in a heatstroke dehydration model - A randomized, single-blind, placebo-controlled, two-periods cross-over comparative trial -

The effect of the test diet on the absorption and excretion of water and electrolytes in the body in a heatstroke dehydration model - A randomized, single-blind, placebo-controlled, two-periods cross-over comparative trial - - The effect of the test diet on the absorption and excretion of water and electrolytes in the body in a heatstroke dehydration model - A randomized, single-blind, placebo-controlled, two-periods cross-over comparative trial -

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056233

Enrollment

Registered

2024-12-17

Start date

2025-01-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

The test diet of the equal amount of body weight loss after sauna stress is separately given by three times. The placebo diet of the equal amount of body weight loss after sauna stress is separately g

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. Males aged 20 or older on the day of consent acquisition. 2. Body weight is over 50 kg. 3. Percent Body fat is below or equal to 25 percent. 4. Those who can use smartphones or PC to record a digital diary. 5. Received a sufficient explanation for the study objective, and voluntarily joined the study with the agreement to informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who regularly use foods or supplements with functional health claims that may affect the study outcome three times or more a week and cannot stop them from the time of consent acquisition (e.g., health foods containing capsaicin, spices, or other strong stimulants that have effects such as improving blood flow, increasing body temperature, or inducing sweating). 2. Currently receiving drug therapy (however as-needed medication is acceptable.). 3. Heavy alcohol drinker with a habit of drinking over an average of 40 g/day per week. 4. Those who have difficulty with blood sampling. 5. Those who have a tattoo. 6. Those who feel difficulty with sweating in a sauna bath. 7. Subjects without body weight fluctuation due to sweating. 8. Those who can't enter a sauna bath for ten minutes three times. 9. Those who can't enter an one person sauna bath due to claustrophobia. 10. Those who have a scar for a burn injury in a wide area of the body. 11. Those who have severe diseases or a history of severe diseases in the heart, liver, kidney, or digestive organs. 12. Those who have allergies to drugs or foods. 13. Those who are participating in clinical studies of other drugs or health foods, within 4 weeks after the end of the study, or who plan to participate in other clinical studies after consenting to participate in the study. 14. Those who donated blood components or whole blood of 200 mL within one month before the start of the study. 15. Those who have blood donation above 400 mL within three months before the start of the study. 16. Those whose total blood collection volume, including the planned volume for the study and the volume collected in the previous 12 months, exceeds 1200 mL prior to the initiation of the study. 17. Those who are deemed unsuitable for participation in the study by the principal investigator or the sub-investigator.

Design outcomes

Primary

Measure	Time frame
Changes in body weight after sauna stress	—

Secondary

Measure	Time frame
Hematologic test Blood biochemistry test Urinalysis Physiological test Fractional Excretion of Sodium Electrolyte balance Water balance Physical symptoms	—

Countries

Japan

Contacts

Public ContactYoshitada Hira

IMEQRD Co., Ltd. Planning and Sales Department

clinical-trial@imeqrd.co.jp03-6704-5968

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026