hypertensive disorder of Pregnancy
Conditions
Interventions
Pregnant women with hypertensive disorder of pregnancy will be included. Blood sampling, vascular endothelial function test, and stress evaluation will be performed at diagnosis, before delivery, and
Sponsors
Aichi Medical University School of Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Pregnant women with hypertensive disorder of pregnancy: Pregnant women with hypertensive disorder of pregnancy (HDP) Normal pregnant women: Uncomplicated pregnant women (after 36 weeks) Non-pregnant women: Non-pregnant women without complications
Exclusion criteria
Exclusion criteria: Pregnant women with hypertensive disorder of pregnancy: non-pregnant BMI less than 18 and greater than 25. Pregnant women with a chronic disease or history of a chronic disease that could affect pregnancy (diabetes, cardiac disease, respiratory disease, endocrine disease, etc.) Normal pregnant women: BMI less than 18, BMI greater than 25 Non-pregnant women: BMI less than 18, BMI greater than 25
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate blood orexin levels in normal pregnant women and pregnant women with hypertensive disorder of pregnancy and in non-pregnant women. (Normal pregnant women at 34 weeks. Pregnant women with hypertensive disorder of pregnancy will be evaluated at the time of disease onset.) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate blood ROS levels, vascular endothelial function, and stress levels in normal pregnant women and pregnant women with hypertensive disorder of pregnancy and in non-pregnant women.(Normal pregnant women at 34 weeks. Pregnant women with hypertensive disorder of pregnancy will be evaluated at the time of disease onset.) | — |
Countries
Japan
Contacts
Public Contacttomohito okamoto
Aichi Medical University School of Medicine Departments of Obstetrics and Gynecology
Outcome results
None listed