Analysis of myokine dynamics due to relaxation of the oblique abdominal muscles -Randomised crossover trial-

Analysis of myokine dynamics due to relaxation of the oblique abdominal muscles - Analysis of myokine dynamics due to relaxation of the oblique abdominal muscles

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056162

Enrollment

Registered

2024-11-15

Start date

2024-11-06

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteers

Interventions

4.9 N-first sequence: In period 1, a 10-min focal manual loading procedure at 4.9 N is applied to the bilateral lateral abdominal wall during slow guided lateral trunk movement. After a 7-day interval

the planned difference is the target fingertip force. 0.49 N-first sequence: In period 1, participants receive a 10-min movement-matched 0.49 N control procedure applied to the bilateral lateral abdom

the planned difference is the target fingertip force.

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1 Men aged 20 to 39 at the time of obtaining consent 2 Individuals with a body mass index (BMI) ranging from 18.5 to 25

Exclusion criteria

Exclusion criteria: 1 Individuals receiving treatment for an underlying medical condition. 2 Individuals deemed inappropriate for the research by the supervising physician due to the significant mental and physical load of participation. 3 Individuals deemed unfit by the study's supervisor

Design outcomes

Primary

Measure	Time frame
Serum myokine concentrations for 15 items	—

Secondary

Measure	Time frame
1) Ultrasound elastography assessment of lateral abdominal wall tissue stiffness Tissue stiffness of the subcutaneous fat, fascia, external oblique muscle, and internal oblique muscle is assessed by ultrasound elastography at the anterior, midaxillary, and posterior axillary lines before, immediately after, and 15 min after the intervention. 2) Serum myoglobin concentrations Serum myoglobin concentrations are assessed before the intervention, immediately after the intervention, and 5, 10, and 15 min after the intervention. Serum myoglobin was added as a secondary outcome in protocol version 1.2 dated 17 April 2025.	—

Measure

Time frame

1) Ultrasound elastography assessment of lateral abdominal wall tissue stiffness Tissue stiffness of the subcutaneous fat, fascia, external oblique muscle, and internal oblique muscle is assessed by ultrasound elastography at the anterior, midaxillary, and posterior axillary lines before, immediately after, and 15 min after the intervention. 2) Serum myoglobin concentrations Serum myoglobin concentrations are assessed before the intervention, immediately after the intervention, and 5, 10, and 15 min after the intervention. Serum myoglobin was added as a secondary outcome in protocol version 1.2 dated 17 April 2025.

—

Countries

Japan

Contacts

Public ContactHaruka Amitani

Kagoshima University Graduate School of Medical and Dental Sciences Department of Psychosomatic Internal Medicine

amitani@m3.kufm.kagoshima-u.ac.jp0992755751

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026