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The Utility of MRI Cortical Imaging for the Evaluation of the Sacroiliac Joint in Patients with Spondyloarthritis

The Utility of MRI Cortical Imaging for the Evaluation of the Sacroiliac Joint in Patients with Spondyloarthritis - The Utility of MRI Cortical Imaging for the Evaluation of the Sacroiliac Joint in Patients with Spondyloarthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000056152
Enrollment
64
Registered
2024-11-14
Start date
2024-10-29
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spondyloarthritis

Interventions

MRI cortical bone imaging

Sponsors

Keio University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 18 years or older with spondyloarthritis who were referred for sacroiliac joint MRI by the Rheumatology and Collagen Disease Department based on the need for imaging evaluation.

Exclusion criteria

Exclusion criteria: - Individuals under 18 years of age - Individuals unsuitable for MRI (e.g., those with metal implants such as pacemakers, claustrophobia, etc.) - Individuals who do not consent to participate in the study - Individuals who are pregnant or may be pregnant - Individuals deemed unsuitable by the principal or co-investigators

Design outcomes

Primary

MeasureTime frame
In each MRI sequence, the presence or absence of characteristic SpA findings such as bone erosion, ankylosis, fat degeneration, and bone buds - will be evaluated. The concordance rate, sensitivity, and specificity between sequences will then be calculated.

Secondary

MeasureTime frame
If CT images are available, similar comparisons and analyses will also be performed using CT. To support the primary evaluation items, SNR and CNR will be calculated for each sequence, and these quantitative values will be compared and examined. Exploratory evaluation items (and their indicators/evaluation methods): Appropriate parameters for cortical bone imaging, as well as potential new insights or methodologies in imaging diagnostics, will be visually and qualitatively assessed.

Countries

Japan

Contacts

Public ContactManabu Hase

Keio University, School of Medicine Department of Radiology

hase@rad.med.keio.ac.jp03-3353-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026