Ochronosis
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Persons who have received an explanation of this study, understand it, and agree to participate in the study of their own free will (persons who have given their informed consent). (2) Persons who are recognized the symptom of ochronosis. (3) Persons who are able to fill out the consent form and other documents.
Exclusion criteria
Exclusion criteria: (1) Persons with a history of severe hepatic disorder, renal disorder, or myocardial infarction. (2) Persons with severe anemia. (3) Persons with a keloid constitution (scars easily become red and swollen and are difficult to heal). (4) Persons who have diabetes mellitus. (5) Persons who are taking antithrombotic medicines. (6) Pregnant, lactating mothers and those who plan to become pregnant during the study period. (7) Persons with cold symptoms or fever of 37.5 degrees Celsius or higher (Exclusion criteria only on the day of the visit; temperature will be checked at the reception desk). (8) Others whom the doctors involved in the research deem inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparative analysis of gene expression between ochronosis sites and normal skin sites. | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of interaction between skin condition and gene expression in ochronosis sites and normal skin sites. | — |
Countries
Japan
Contacts
POLA Chemical Industries, Inc. Frontier Research Center