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Research of skin mechanism in the hyperpigmentation

Research of intracutaneous mechanism in the ochronosis - Research of intracutaneous mechanism in the ochronosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000056141
Enrollment
5
Registered
2024-11-13
Start date
2024-10-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ochronosis

Interventions

None listed

Sponsors

POLA Chemical Industries, Inc.
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: (1) Persons who have received an explanation of this study, understand it, and agree to participate in the study of their own free will (persons who have given their informed consent). (2) Persons who are recognized the symptom of ochronosis. (3) Persons who are able to fill out the consent form and other documents.

Exclusion criteria

Exclusion criteria: (1) Persons with a history of severe hepatic disorder, renal disorder, or myocardial infarction. (2) Persons with severe anemia. (3) Persons with a keloid constitution (scars easily become red and swollen and are difficult to heal). (4) Persons who have diabetes mellitus. (5) Persons who are taking antithrombotic medicines. (6) Pregnant, lactating mothers and those who plan to become pregnant during the study period. (7) Persons with cold symptoms or fever of 37.5 degrees Celsius or higher (Exclusion criteria only on the day of the visit; temperature will be checked at the reception desk). (8) Others whom the doctors involved in the research deem inappropriate.

Design outcomes

Primary

MeasureTime frame
Comparative analysis of gene expression between ochronosis sites and normal skin sites.

Secondary

MeasureTime frame
Analysis of interaction between skin condition and gene expression in ochronosis sites and normal skin sites.

Countries

Japan

Contacts

Public ContactKazuki Nakayama

POLA Chemical Industries, Inc. Frontier Research Center

kazuki-nakayama@pola.co.jp0458267232

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026