Levodopa and chlorpromazine combination therapy for treatment of primary dystonia
Conditions
Interventions
chlorpromazine group On the first day, we prescribe after breakfast, and order to continue for 2 weeks. After 2 weeks continuous tratmenta, CP 5mg after breakfast, CP 5mg aftre linch, a total of CP
Sponsors
Kumamoto Neurosurgical Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Cervical dystonia and blepharospasm was clinically diagnosed according to the definition by Fahn. (Fahn S.Concept and classification of dystonia. Adv Neurol 1988;50:1-8) Written informed consent was obtained.
Exclusion criteria
Exclusion criteria: All participants were examined by a single movement disorder specialist who performed general physical and neurological examinations,laboratory tests, and brain magnetic resonance imaging to exclude othe cause of dystonia, includinga birth injury anf head trauma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A single movement disorder specialist recorded the participants clinical symptoms with a video camera to assess the objective signs. Aftere that, participants evaluated their subjective clinical signs usinga a visual analog scale (VAS) | — |
Countries
Japan
Contacts
Public ContactNobuhiro Inoue
Kumamoto Neurosurgical Hospital Neurosurgery
Outcome results
None listed