Investigation of the association between serum uric acid levels and atherosclerotic cardiovascular disease risk using the Hisayama study score

Correlation between serum uric acid levels and atherosclerotic cardiovascular disease risk: a multivariate analysis using the Hisayama study score - CUSHION-HART Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000056100

Enrollment

5984

Registered

2024-11-08

Start date

2024-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerotic cardiovascular disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese adults aged 40-79 years Underwent health check-ups between 2020 and 2022 Provided consent for study participation Had complete data available for serum uric acid levels and ASCVD risk calculation

Exclusion criteria

Exclusion criteria: Individuals with a history of ASCVD Individuals under 40 years old or 80 years old and above Individuals with incomplete data for serum uric acid levels or ASCVD risk calculation Individuals who did not provide consent for study participation

Design outcomes

Primary

Measure	Time frame
Correlation between serum uric acid levels and atherosclerotic cardiovascular disease (ASCVD) risk	—

Secondary

Measure	Time frame
Stratification analysis of ASCVD risk by serum uric acid quartiles Independent association between serum uric acid levels and ASCVD risk after adjusting for known ASCVD risk factors Gender differences in the association between serum uric acid levels and ASCVD risk Correlation between serum uric acid levels and individual ASCVD risk factors (age, blood pressure, lipid profile, diabetes status, etc.) Analysis of predictors of serum uric acid levels with ASCVD risk as an independent variable	—

Measure

Time frame

Stratification analysis of ASCVD risk by serum uric acid quartiles Independent association between serum uric acid levels and ASCVD risk after adjusting for known ASCVD risk factors Gender differences in the association between serum uric acid levels and ASCVD risk Correlation between serum uric acid levels and individual ASCVD risk factors (age, blood pressure, lipid profile, diabetes status, etc.) Analysis of predictors of serum uric acid levels with ASCVD risk as an independent variable

—

Countries

Japan

Contacts

Public ContactTakashi Matsuyama

Iwata City Hospital Renal Division, Department of Internal Medicine

matsuyamatks@gmail.com0538-38-5000

Outcome results