Exploratory study on the effects of short-chain aldehydes on liver tissue

Exploratory study on the effects of short-chain aldehydes on liver tissue - Exploratory study on the effects of short-chain aldehydes on liver tissue

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000056085

Enrollment

Registered

2024-11-07

Start date

2024-11-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individuals aged 18 and older hospitalized for scheduled liver resection

Exclusion criteria

Exclusion criteria: Individuals diagnosed with hepatitis B or hepatitis C. Individuals taking oral steroid medications. Individuals scheduled for liver transplantation.

Design outcomes

Primary

Measure	Time frame
plasma glyceraldehyde	—

Secondary

Measure	Time frame
-Histological severity of steatotic liver disease -Glyceraldehyde and methylglyoxal content of liver tissue -Glucose tolerance (blood glucose and HbA1c) -Presence of short-chain aldehydes and DNA adducts in liver tissue -Markers of liver fibrosis	—

Countries

Japan

Contacts

Public ContactYoko Ueba

Graduate School of Medicine, Kyoto University Department of Diabetes, Endocrinology and Nutrition

yokoueba@kuhp.kyoto-u.ac.jp0757513560

Outcome results