Patients with neurological disorders that may cause autonomic neuropathy Examples: Parkinson'
Conditions
Interventions
Cerebral blood flow is measured by near-infrared spectroscopy using HOT-2000 manufactured by NeU.
Sponsors
Hamamatsu University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with neurological diseases that may cause autonomic neuropathy Examples: Parkinson's disease, dementia with Lewy bodies, pure autonomic failure, multiple system atrophy, corticobasal degeneration, progressive supranuclear palsy, spinocerebellar degeneration, familial amyloid polyneuropathy, autoimmune autonomic ganglionopathy, diabetic neuropathy, Sjogren's syndrome, paraneoplastic neurologic syndromes, autoimmune central nervous system inflammatory disease, vasculitis syndrome
Exclusion criteria
Exclusion criteria: Pregnant or at risk of pregnancy. Patients with stroke or with a history of stroke. Patients with neuroendocrine tumor. Patients who are not able to cross their legs, push, hold a standing position, and walk. Patients who are judged by the investigator to be inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| concentration of oxygenated hemoglobin | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum BDNF, serum GFAP, serum UCH-L1, serum NfL, MMSE, FAB | — |
Countries
Japan
Contacts
Public ContactAkiyuki Takenouchi
Hamamatsu University School of Medicine department of neurology
Outcome results
None listed