Healthy adults
Conditions
Interventions
Participants will consume 2 capsules of the test supplement once daily with water or warm water without chewing.
Participants will consume 2 capsules of the placebo supplement once daily with water
Sponsors
IMEQRD Co. Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Age: 40 years or older, but younger than 65 years. 2.Men and women of Japanese nationality. 3.BMI between 18.5 kg/m2 and 30.0 kg/m2. 4.IOP less than 20.0 mmHg at the time of screening. 5.Capability to enter data into an electronic diary via a smartphone or PC. 6.Individuals who have received a sufficient explanation about the study's purpose and content, fully understood it, voluntarily consented to participate and provided written consent.
Exclusion criteria
Exclusion criteria: 1.Receiving treatment for any disease or taking medication (on-demand use allowed). 2.Undergoing dietary or exercise therapy under medical supervision. 3.History of eye surgery (retinal detachment, LASIK, ICL) or eye diseases, including normal-tension glaucoma. 4.Severe liver, kidney, heart, respiratory, endocrine, metabolic diseases, or history thereof. 5.History of gastrointestinal surgery (appendectomy allowed). 6.Using medications, quasi-drugs, health foods, supplements, or foods with functional claims for eye care. 7.Regularly (three or more times a week) consuming over-the-counter medications, quasi-drugs, health foods, supplements, foods for specified health uses, or foods with functional claims (participation allowed if stopped post-consent). 8.Current or past history of drug or food allergies. 9.Eye allergy symptoms from November to March (including those at risk). 10.Excessive alcohol consumption (pure alcohol intake of 40g or more per day). 11.Excessive smoking (21 or more cigarettes per day). 12.Engaged in shift work with night shifts. 13.Planning significant lifestyle changes (diet, sleep, exercise) during the study period due to long-term travel, etc. 14.History of vagal reactions or frequent anemia symptoms after blood collection. 15.Currently pregnant or breastfeeding, or planning to become pregnant during the study period. 16.Participating in other clinical trials, or within 4 weeks of this study, or planning to participate in another clinical trial post-consent. 17.Donated blood components or 200 mL of whole blood within one month before the study. 18.Donated 400 mL of whole blood within three months before the study. 19.Total blood donation volume, including this study, exceeds 1200 mL within 12 months prior. 20.Considered inappropriate for the study by the principal or sub-investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure (IOP) | — |
Secondary
| Measure | Time frame |
|---|---|
| Contrast Sensitivity Quality of Life (QOL) Questionnaires (NEI VFQ-25, VAS, Anti-Aging QOL) Cellular Activity | — |
Countries
Japan
Contacts
Public ContactYoshitada Hira
IMEQRD Co., Ltd. Planning and Sales Department
Outcome results
None listed