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Influence of ovarian hormones on inflammatory responses and indirect markers of muscle injury following exercise-induced muscle damage

Influence of ovarian hormones on inflammatory responses and indirect markers of muscle injury following exercise-induced muscle damage - Influence of ovarian hormones on inflammatory responses and indirect markers of muscle injury following exercise-induced muscle damage

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000056015
Enrollment
36
Registered
2024-11-01
Start date
2022-04-07
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise-induced muscle damage

Interventions

Eccentric exercise using non-dominant arms 10 sets of maximal voluntary isokinetic eccentric exercises elbow flexors at a velocity of 90 degree/s for ROM from 90 degree-0 degree flexion, indicating

Sponsors

Teikyo University of Science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All participant 1) no resistance training or vigorous exercises for at least 6 months before the study 2) no musculoskeletal injury reported in the last 6 months 3) no existing disease and metabolic or hormonal disorder 4) no regular use of medication or dietary supplements that could affect the results 5) no smoking Female participant 1) regular menstrual cycle length (25-38 days) 2) no oral contraceptives administered exercises for at least 6 months 3) no pregnancies in the previous year, no period of lactation

Exclusion criteria

Exclusion criteria: who do not comply with the inclusion criteria

Design outcomes

Primary

MeasureTime frame
Blood samples are collected at pre- and 4,48 and 96 h postexercise to analyze estradiol and progesterone concentrations, leukocyte count and fractionation, interleukin-6, and creatine kinase activity. Also assess the maximal voluntary isometric contraction torque of elbow flexion, range of motion in elbow joint, upper-arm circumference, and muscle soreness as indirect muscle damage markers at pre-; immediately post; and 4,48,96 h postexercise.

Countries

Japan

Contacts

Public ContactAkiko Funaki

Teikyo University of Science Faculty of Medical Sciences

a-funaki@ntu.ac.jp0554-63-4411

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026