Effects of exercise and soy peptide intake on physical frailty improvement in community-dwelling physically pre-frail older adults: a randomized controlled trial

Effects of exercise and soy peptide intake on physical frailty improvement in community-dwelling physically pre-frail older adults: a randomized controlled trial - Intervention trial of exercise and nutritional support in physically pre-frail older adults

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056010

Enrollment

Registered

2024-11-01

Start date

2024-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frail or Pre-frail older adults (65years old or more)

Interventions

Intervention group: Perform original community-based exercise program for 10 sessions over 3 months. In addition, only the intervention group will consume 6 g of soy peptide per day for 3 months. On d

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) older adults who have participated in cohort studies, 2) Native speaker 3) No limitations on age, sex, and medications.

Exclusion criteria

Exclusion criteria: 1)Doctors orders to stop exercise 2) Medically advised not to participate in exercise 3) Dementia 4)Persons with soy allergy. 5) Persons with birch allergy.

Design outcomes

Primary

Measure	Time frame
Weight loss, walking speed, grip strength, exhaustion, exercise habits, Kihon checklist	—

Secondary

Measure	Time frame
Frailty-related items: oral function, gait, posture, general cognitive function, motor function test, body composition, employment status, work motivation, subjective health perspective, nutrition intake, food diversity score, sleep status, biochemical data (AST, ALT, gamma-GT, uric acid, albumin, triglycerides, total cholesterol, HDL cholesterol, LDL cholesterol, blood glucose, HbA1c, creatine kinase, urea nitrogen, creatinine, CRP, calcium, inorganic phosphorus,), physical activity, depression, life spread, basic checklist, flexibility, 3D motion analysis, oral function	—

Measure

Time frame

Frailty-related items: oral function, gait, posture, general cognitive function, motor function test, body composition, employment status, work motivation, subjective health perspective, nutrition intake, food diversity score, sleep status, biochemical data (AST, ALT, gamma-GT, uric acid, albumin, triglycerides, total cholesterol, HDL cholesterol, LDL cholesterol, blood glucose, HbA1c, creatine kinase, urea nitrogen, creatinine, CRP, calcium, inorganic phosphorus,), physical activity, depression, life spread, basic checklist, flexibility, 3D motion analysis, oral function

—

Countries

Japan

Contacts

Public ContactMasakazu Imaoka

Osaka Kawasaki Rehabilitation University Department of Rehabilitation

imaokamasakazu@gmail.com07244466700

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026