Evaluation of the Impact of Bariatric Surgery on Bronchial Asthma Control in Obesity-Related Bronchial Asthma Patients: A Prospective Observational Study

Evaluation of the Impact of Bariatric Surgery on Bronchial Asthma Control in Obesity-Related Bronchial Asthma Patients: A Prospective Observational Study - Evaluation of the Impact of Bariatric Surgery on Bronchial Asthma Control in Obesity-Related Bronchial Asthma Patients: A Prospective Observational Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000056000

Enrollment

Registered

2024-10-30

Start date

2024-06-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchial asthma, obese, obesity-related bronchial asthma.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 18 years of age or older Ongoing bronchial asthma treatment at the time of Bariatric Surgery First Bariatric Surgery

Exclusion criteria

Exclusion criteria: Pacemaker patients Patients with Nt-pro BNP 125ng/dl or higher Severe psychiatric illness Patients with cancer Obesity due to endocrine disorders or drugs (secondary obesity)

Design outcomes

Primary

Measure	Time frame
Pre- and postoperative change in ACT score (3, 6, and 12 months postoperatively)	—

Secondary

Measure	Time frame
Pre- and postoperative change in FEV1 (3, 6, and 12 months postoperatively) Pre- and post-operative change in NO levels (3, 6, and 12 months post-operatively) ACT evaluation of asthma phenotype Type 2 inflammation group and Non-Type 2 inflammation group (3,6,12 months postoperatively) Number of Rescue SABA use based on ACT (evaluated based on ACT score data) (3,6,12 months post-op) %TWL, %EWL and ACT evaluation (3,6,12 months postoperatively) Body composition values and ACT evaluation (3, 6, and 12 months postoperatively) ACT evaluation with and without CPAP intervention and compliance evaluation group (3, 6, and 12 months postoperatively) Pre- and postoperative changes in adiponectin and leptin levels (12 months postoperatively) The above study was performed with and without the use of GLP-1 The above study excluding patients with Brinkman Index 400 or higher	—

Measure

Time frame

Pre- and postoperative change in FEV1 (3, 6, and 12 months postoperatively) Pre- and post-operative change in NO levels (3, 6, and 12 months post-operatively) ACT evaluation of asthma phenotype Type 2 inflammation group and Non-Type 2 inflammation group (3,6,12 months postoperatively) Number of Rescue SABA use based on ACT (evaluated based on ACT score data) (3,6,12 months post-op) %TWL, %EWL and ACT evaluation (3,6,12 months postoperatively) Body composition values and ACT evaluation (3, 6, and 12 months postoperatively) ACT evaluation with and without CPAP intervention and compliance evaluation group (3, 6, and 12 months postoperatively) Pre- and postoperative changes in adiponectin and leptin levels (12 months postoperatively) The above study was performed with and without the use of GLP-1 The above study excluding patients with Brinkman Index 400 or higher

—

Countries

Japan

Contacts

Public ContactMITSUHIRO SUMITANI

Chibune General Hospital, Aijinkai Healthcare Corporaion Department of Sleep, Respiratory and Rehabilitation Medicine

sumytany@nifty.com06-6471-9541

Outcome results