An observational study on the association between oral microflora and ventilator-associated pneumonia in Vietnam

An observational study on the association between oral microflora and ventilator-associated pneumonia in Vietnam - Oral microbiome study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000055978

Enrollment

Registered

2024-10-29

Start date

2024-11-14

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ventilator-associated pneumonia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) 18 years of age or older 2) Patients who are intubated within 48 hours of admission and who will be admitted to the ICU within 48 hours of admission 3) Patients who have obtained consent to participate in the study from the patient or a surrogate

Exclusion criteria

Exclusion criteria: 1) Patients with pneumonia prior to intubation 2) Patients who have been extubated/left ICU/deceased within 48 hours of intubation 3) Patients with trauma to the head, neck, or face 4) Patients whose oral cavity is contaminated with blood 5) Patients with trauma or signs of infection in the oral cavity prior to intubation 6) Those who are judged as unsuitable by the principal investigator or the project leader

Design outcomes

Primary

Measure	Time frame
Differences in oral flora in intubated patients with and without VAP using real-time PCR: during the first 7 days from case enrollment	—

Secondary

Measure	Time frame
Aassociation of bacterial flora in sputum and oral specimens in patients with VAP	—

Countries

Japan,Asia(except Japan)

Contacts

Public ContactSho Saito

Japan Institute for Health Security Disease Control and Prevention Center

oralmicroflora@jihs.go.jp0332027181

Outcome results