Effects of pre-meal gum chewing on the autonomic nervous system

Effects of pre-meal gum chewing on the autonomic nervous system: A randomized cross-over trial - Effects of pre-meal gum chewing on the autonomic nervous system: A randomized cross-over trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000055946

Enrollment

100

Registered

2024-10-25

Start date

2025-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Japanese adults

Interventions

10 minutes of free gum chewing before lunch, and no intervention No intervention, and 10 minutes of free gum chewing before lunch

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Persons who obtained written informed consent before the participation, and more can measure habitual chewing ability.

Exclusion criteria

Exclusion criteria: Suffering from disease medicine that affects the autonomic nervous system Receiving dietary instructions or guidance Have a pacemaker Difficulty deglutition

Design outcomes

Primary

Measure	Time frame
autonomic nervous system (LF/HF): from pre-meal to after 90 minutes meal	—

Secondary

Measure	Time frame
flash glucose monitoring	—

Countries

Japan

Contacts

Public ContactToshiko Kuwano

University of Shizuoka School of Food and Nutritional Science

kuwano@u-shizuoka-ken.ac.jp054-264-5513

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026