Middle-aged and older adults
Conditions
Interventions
1-year multicomponent exercise training program
1-year stretching program
Sponsors
University of Tsukuba
1) National Institute of Advanced Industrial Science and Technology 2) Jichi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Individuals who participated in the 5-year follow-up of the prospective cohort study (Registry No. UMIN000034741) conducted earlier. 2) Individuals who fall under GFR stages 1 to 3b (estimated glomerular filtration rate of 30 mL/min/1.73 m^2 or higher). 3) Individuals who can agree to the terms of use of the Tsukuba Memorial Hospital Medical Fitness Center Phoenix.
Exclusion criteria
Exclusion criteria: 1) Individuals who have been advised by a doctor to restrict physical activity. 2) Individuals who are currently suffering from a serious illness or have a history of severe diseases (e.g., cardiovascular diseases). 3) Individuals who are judged to have issues that would hinder the progression of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimated glomerular filtration rate (eGFR) slope | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Phosphate metabolism 2. Cardiovascular measurements 3. Renal duplex ultrasonography 4. Endothelial function 5. Blood biomarkers 6. Urinary biomarkers 7. Physical function 8. Daily physical activity and sedentary behavior 9. Body composition 10. Magnetic resonance imaging 11. Cognitive function 12. Dietary assessments 13. Sleep, Mental, and Pain status | — |
Countries
Japan
Contacts
Public ContactKeisei Kosaki
University of Tsukuba Institute of Health and Sports Science
Outcome results
None listed