Evaluation of the improvement in physical function by high 11S globulin content soybeans in healthy middle-aged and elderly individuals with low physical activity levels

Evaluation of the improvement in physical function by high 11S globulin content soybeans in healthy middle-aged and elderly individuals with low physical activity levels - Evaluation of the improvement in physical function by high 11S globulin content soybeans in healthy middle-aged and elderly individuals with low physical activity levels

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000055799

Enrollment

Registered

2025-01-06

Start date

2024-12-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy middle-aged and elderly Individuals

Interventions

Specifics of the intervention act (high 11S globulin content soybeans in blended diet 100g /day, administration period of 28 days) Criteria for modification of the intervention

discontinuation of the intervention if any discomfort (allergic symptoms, etc.) occurs due to ingestion Criteria for discontinuation or completion of the intervention (prophylaxis, testing, etc.)

discontinuation if any intake-related discomfort (allergic symptoms, etc.) occurs Specifics of the intervention act (milk protein in blended diet 100g /day, administration period of 28days) Criteri

discontinuation if any intake-related discomfort (allergic symptoms, etc.) occurs Specifics of the intervention act (placebo in blended diet 100g /day, administration period of 28days) Criteria for

discontinuation if any intake-related discomfort (allergic symptoms, etc.) occurs

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Over 45 years old Female (If it is not possible to gather only female participants, males may also be included) Individuals who have given their consent Individuals with low physical activity level

Exclusion criteria

Exclusion criteria: Individuals with myogenetic diseases Individuals with moderate or severe renal dysfunction (including those with diabetes) Individuals with dietary protein restrictions Individuals receiving medications that affect muscles, such as corticosteroids Individuals with allergies (especially soy, milk and pollen allergies) Individuals taking health supplements containing soy or protein Individuals with pacemakers, claustrophobia, or other conditions that prevent MRI examinations Individuals who refuse to participate in the study Individuals deemed by the principal investigator to be unable to participate in the study

Design outcomes

Primary

Measure	Time frame
Lean body mass (Muscle mass) Quadriceps Volume by MRI Muscle Strength Walking Time and Speed	—

Secondary

Measure	Time frame
Muscle Atrophy Marker Oxidative Stress Marker	—

Countries

Japan

Contacts

Public ContactTakeshi Nikawa

The University of Tokushima Graduate School Graduate School of Biomedical Sciences

nikawa@tokushima-u.ac.jp088-633-9248

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026