The efficacy of Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) and External Oblipue Intercostal Block (EOIB) for laparoscopic cholecystectomy: a single-blinded randomised controlled trial

The efficacy of Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) and External Oblipue Intercostal Block (EOIB) for laparoscopic cholecystectomy: a single-blinded randomised controlled trial - The efficacy of Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) and External Oblipue Intercostal Block (EOIB) for laparoscopic cholecystectomy: a single-blinded randomised controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000055796

Enrollment

Registered

2024-10-10

Start date

2024-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic cholecystectomy

Interventions

Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) External Oblique Intercostal Block(EOIB)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing laparoscopic cholecystectomy Patients classified as American Society of Anesthesiologists 1~2 Patients aged 20~85 years Patients who have given written consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients undergoing emergency surgery on the day of the procedure Patients who are chronically using opioids Patients who are allergic to local anaesthetics Patients who are unable to give consent Patients with abnormal coagulation function Patients receiving antithrombotic therapy and who do not meet the criteria for a sufficient drug withdrawal period in accordance with the Guidelines for Regional Anesthesia and Nerve Block during Antithrombotic Therapy Patients judged by the principal investigator or sub-investigator to be unsuitable for the study

Design outcomes

Primary

Measure	Time frame
Values and changes 1 and 2 days after surgery compared to pre-surgery values for QOR-15	—

Secondary

Measure	Time frame
NRS at 2, 12, 24 and 48 hours after surgery skin sensitivity evaluation using the pinprick test at 2 hours	—

Countries

Japan

Contacts

Public ContactTakayuki Yamanaka

Nara Prefecture General Medical Center Anaesthesiology

yamachan_19881120@yahoo.co.jp0742-46-6001

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026