Papillary thyroid carcinoma
Conditions
Interventions
None listed
Sponsors
Nippon Medical School
Kuma Hospital Shinshu University Yamashita Thyroid Hospital Nagoya University Hospital The Third Hospital of Jikei University School of Medicine Kobe University Hospital Showa University Northern Yokohama Hospital Hiratsuka Kyosai Hospital Gunma University Hospital Fukushima Medical University Tokyo Women'
s Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with low-risk PTC diagnosed by ultrasonography and fine needle aspiration biopsy, with a primary tumor size of 15 mm or less, who chose AS after receiving sufficient explanation and giving informed consent regarding the management strategy
Exclusion criteria
Exclusion criteria: Patients with evident extrathyroidal extension, lymph node metastasis, or distant metastasis Patients with the following comorbidities: Graves' disease, other forms of thyrotoxicosis, ischemic heart disease, arrhythmia, or osteoporosis Patients already undergoing AS for papillary thyroid carcinoma Patients deemed to lack the capacity to make decisions regarding participation in the study Other patients considered unsuitable for participation in the study by the principal investigator or co-investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression rate (tumor growth, occurrence of lymph node metastasis) compared between the group undergoing thyrotropin suppression therapy and the group not receiving it for patients who chose active surveillance (AS) for low-risk papillary thyroid carcinoma (PTC) after October 2024 through shared decision-making (SDM). | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events and quality of life (QoL) compared between the group undergoing thyrotropin suppression therapy and the group not receiving it for patients who chose AS for low-risk PTC after October 2024 through SDM. | — |
Countries
Japan
Contacts
Public ContactIwao Sugitani, MD, PhD (Endocrine Surgery)
Nippon Medical School Department of Endocrine Surgery
Outcome results
None listed