None listed
Conditions
Interventions
Apply skin external preparation (BH318) to the face twice a day for 4wks.
Apply placebo to the face twice a day for 4wks.
Sponsors
Kao Corporation
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Skin condition survey, efficacy test Common eligibility 1. Japanese women between the ages of 20 and 59 2. Person who are aware of their facial skin type as dry skin. 3. Person who are aware that they have sensitive skin. 4. Person who are relatively simple in their usual care after washing their face. 5. Person who understand the measurement contents and schedule of this research and can follow the various restrictions and instructions given by the researcher during the period of cooperation in participating in the research. 6. Person who are able to obtain written consent based on their own free will prior to the start of the research. Eligibility for the efficacy test only 1. Top 40 participants in the skin condition survey who have a high desquamation/scaling score based on visual observation by doctor (the score must be 0.5 or higher).
Exclusion criteria
Exclusion criteria: 1. Person who have scars, eczema or other skin problems at the test site 2. Person who have severe itching and redness on the skin of the test site 3. Person who have been diagnosed with skin diseases such as atopic dermatitis or sebum deficiency on the test site and have visited the hospital or used medicines within a year 4. Person who have undergone cosmetic treatment (chemical peeling, laser treatment, etc.) on the test site or have undergone cosmetic treatment (cosmetic surgery, collagen injection, etc.) in the past one year from the time of explanation. 5. Person who are taking sleeping pills, antiallergic drugs, painkillers, hormonal agents, laxatives, gastric acid secretion inhibitors, or other medicines for illnesses on a regular basis. 6. Person who are being treated for diseases that may affect blood flow measurement (hypertension, heart disease, diabetes, Raynaud's disease, rosacea, telangiectasia, etc.) 7. Person who are routinely lose weight or have extremely irregular eating habits. 8. Person with extreme sunburn or person who cannot avoid prolonged outdoor work or sports 9. Person who have a habit of smoking or excessive alcohol consumption. 10. Person who are nursing or pregnant, or who wish to become pregnant during the test period 11. Participants or their family members who are in the following occupations: cosmetics, mass media, research, or clinical trial organization. 12. Person who have participated in a human study within the past 4 weeks. 13. Currently participating in other clinical trials or clinical studies, or planning to participate during the test period. 14. Others who are deemed ineligible by the principal investigator or investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy : Change in desquamation and scaling score based on visual observation by doctor Safety: Incidence of adverse events | — |
Secondary
| Measure | Time frame |
|---|---|
| - Skin capacitance value -Transdermal water vaporization (TEWL value) -Skin blood flow | — |
Countries
Japan
Contacts
Public ContactRyoko Harada
Kao Corporation Human Health Care Products Research
Outcome results
None listed