Adult
Conditions
Interventions
Capsaicin-containing film, 3 sheets a day, 2 weeks
Placebo film, 3 sheets a day, 2 weeks
Sponsors
Yamada Bee Company, Inc.
Research Center for Immunological Analysis, Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Healthy males and females who are at least 50 years old at the time of obtaining consent. 2) Subjects can understand and comply with the rules written in protocol during clinical study period. 3) Subjects whose written informed consent has been obtained.
Exclusion criteria
Exclusion criteria: 1) Subjects diagnosed with oral related diseases such as xerostomia (dry mouth), oral hypofunction. 2) Subjects with hepatic, renal, cardiac, diabetes or other serious diseases. 3) Subjects who judged by a doctor as depression, dementia or mild cognitive impairment. 4) Subjects who have participated in other clinical trials within 84 days prior to the date of consent. 5) Subjects who are judged as unsuitable for this study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral wetness | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary volume Tongue pressure Salivary pH Oral periodontal disease-related bacteria Exhaled gas GOHAI SF-8 Questionnaire | — |
Countries
Japan
Contacts
Public ContactDaisuke Suwa
Yamada Bee Company, Inc. Functional research section, Institute for Bee Products & Health Science, R&D department
Outcome results
None listed