Dry Eye, Healthy Volunteers
Conditions
Interventions
Blinking Exercise
Artifical Tears
Sponsors
Itoh Clinic
Lid and meibomian gland working group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age: 18 years or older, but under 60 at the time of consent. Gender: No restrictions. Ability: Must be able to personally complete and sign the consent form.
Exclusion criteria
Exclusion criteria: Patients with acute eye or eyelid diseases Obvious eyelid or ocular surface diseases (congenital eyelid abnormalities, entropion, ectropion, Sjogren's syndrome) Thyroid eye disease or neurological conditions (e.g., oculomotor nerve palsy, myasthenia gravis, Horner's syndrome) Use of anti-glaucoma eye drops History of eyelid surgery (e.g., ptosis correction, blepharoplasty) or facial fractures Daily use of hard contact lenses Recent eye surgery,IPL,LipiFlow, Botox within 3 months Ocular allergies during testing Judged as unsuitable by the principal investigator or co-investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| palpebral fissure height (mm) | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective Symptoms SPEED Score: Evaluates the frequency and severity of dry eye symptoms, scoring from 0 to 28. Visual Analog Scale (VAS): Independently rates 8 symptoms (dryness, eye fatigue, discomfort, blurred vision, foreign body sensation, pain, heaviness, difficulty opening eyes) from 0 (no symptoms) to 100 (maximum symptoms). Measurements using idra Tear lipid layer thickness (nm) Tear meniscus height (mm) Blink quality (%), complete/incomplete blinks, duration (seconds) Non-invasive tear break-up time (NIBUT first, average) (seconds) Corneal and conjunctival epithelial damage score: Assessed using fluorescein staining (0-9). Tear film break-up time with fluorescein (FBUT) (seconds): Average of 3 measurements. | — |
Countries
Japan
Contacts
Public ContactReiko Arita
Itoh Clinic Ophthalmology
Outcome results
None listed