acute coronary syndrome
Conditions
Interventions
None listed
Sponsors
Kindai University Faculty of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) patients were admitted with ACS (ST-segment elevation myocardial infarction, non-ST-segment elevation myocardial infarction, and unstable angina pectoris); (2) intermediate stenosis in non-culprit lesions on coronary angiography or CCTA; and (3) NIRS-IVUS evaluation for intermediate stenosis after percutaneous coronary intervention.
Exclusion criteria
Exclusion criteria: (1) chronic kidney disease as shown by an estimated glomerular filtration rate <30 ml/min/1.73 m2; (2) presentation with hemodynamic instability; (3) severe valvular heart diseases, (4) left main trunk lesions; (5) lesions that could not be evaluated by NIRS-IVUS for any reason (e.g., tortuous vessels, severe stenosis, and calcification that made catheter passage difficult); and (6) poor image quality that resulted in an inability to perform CCTA or NIRS-IVUS analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In ACS patients who reduced LDL-C to less than 55 mg/dL compared to those who reduced it to between 55 and 70 mg/dL, we will evaluate how the plaques with maxLCBI4mm > 400 and < 400 in non-culprit lesions changed as assessed by NIRS-IVUS. Additionally, we will examine whether there are any changes in lipid markers other than LDL-C in these patients. | — |
Countries
Japan
Contacts
Public ContactKazuyoshi Kakekhi
Kindai University Faculty of Medicine Division of Cardiology
Outcome results
None listed