Impact of inhaled nitric oxide therapy in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation combined with Impella

Impact of inhaled nitric oxide therapy in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation combined with Impella - Impact of inhaled nitric oxide therapy in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation combined with Impella

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000055585

Enrollment

Registered

2024-09-22

Start date

2024-08-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

consecutive patients supported with ECPELLA for CS due to acute myocardial infarction (AMI) and non-compensated heart failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: This study was a single center retrospective observational study and included consecutive patients supported with ECPELLA for CS due to acute myocardial infarction (AMI) and non-compensated heart failure at Kindai University Hospital from September 2019 to March 2024.

Exclusion criteria

Exclusion criteria: Under 20 years of age

Design outcomes

Primary

Measure	Time frame
The primary endpoint was the comparison of 30-day all-cause mortality between patients with iNO and without iNO.	—

Secondary

Measure	Time frame
The secondary endpoints were comparisons of the VA-ECMO withdrawal rate and duration between patients with and without iNO therapy, as well as changes in hemodynamic- and MCS-related parameters after the initiation of iNO therapy.	—

Countries

Japan

Contacts

Public ContactNobuhiro Yamada

Department of Medicine, Kindai University Faculty of Medicine Division of Cardiology

n.0609.yamada@gmail.com+81-72-366-0221

Outcome results