Observational multicenter registry to DEvelop updaTed Echocardiographic Cut-off and algorithm for early deTection of Pulmonary Hypertension

Observational multicenter registry to DEvelop updaTed Echocardiographic Cut-off and algorithm for early deTection of Pulmonary Hypertension - DETECT-PH

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000055583

Enrollment

3000

Registered

2024-09-22

Start date

2024-09-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who underwent right heart catheterization

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years or older at the time of enrollment 2. Patients who underwent echocardiography within 48 hours before or after the right heart catheterization

Exclusion criteria

Exclusion criteria: 1. Patients who received treatment interventions that could affect hemodynamics between the echocardiography and right heart catheterization (such as dialysis, medication administration, etc.) 2. Patients for whom echocardiography could not be performed within 48 hours before or after the right heart catheterization due to scheduling constraints or the clinical system 3. Patients who requested to withdraw from the study or revoked their consent 4. Patients deemed unsuitable for the study by the principal investigator for any other reason

Design outcomes

Primary

Measure	Time frame
The positivity rate of echocardiographic indicators in cases with mean pulmonary artery pressure greater than 20 mmHg as measured by right heart catheterization. The positivity rate of echocardiographic indicators in cases with mean pulmonary artery pressure greater than 20 mmHg, pulmonary artery wedge pressure less than or equal to 15 mmHg, and pulmonary vascular resistance greater than 2 WU as measured by right heart catheterization.	—

Measure

Time frame

The positivity rate of echocardiographic indicators in cases with mean pulmonary artery pressure greater than 20 mmHg as measured by right heart catheterization. The positivity rate of echocardiographic indicators in cases with mean pulmonary artery pressure greater than 20 mmHg, pulmonary artery wedge pressure less than or equal to 15 mmHg, and pulmonary vascular resistance greater than 2 WU as measured by right heart catheterization.

—

Secondary

Measure	Time frame
Correlation between right heart catheterization indicators and echocardiographic indicators. Occurrence of cardiovascular events during the follow-up period. Occurrence of all-cause mortality during the follow-up period. Interventions for pulmonary hypertension during the follow-up period. Physical findings: Changes in WHO/NYHA functional class, 6-minute walk distance, and cardiopulmonary exercise test results from baseline to the end of the observation period.	—

Measure

Time frame

Correlation between right heart catheterization indicators and echocardiographic indicators. Occurrence of cardiovascular events during the follow-up period. Occurrence of all-cause mortality during the follow-up period. Interventions for pulmonary hypertension during the follow-up period. Physical findings: Changes in WHO/NYHA functional class, 6-minute walk distance, and cardiopulmonary exercise test results from baseline to the end of the observation period.

—

Countries

Japan

Contacts

Public ContactKimi Sato

University of Tsukuba Hospital Department of Cardiovascular Medicine

kimisato@md.tsukuba.ac.jp029-853-3143

Outcome results