malocclusion
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy subjects between 18 and 40 years old. 2.Undergoing orthodontic therapy with fixed appliances both in the upper and lower arch with monthly follow-up appointments. 3.In extraction cases patients could be enrolled at least two months after the last extraction. 4.Total initial VSCs levels above the baseline level of 150 ppb.
Exclusion criteria
Exclusion criteria: Patients with active caries, periodontitis (periodontal pockets 3 mm or more), dental fluorosis/ dysplasia of the teeth, syndromes or other abnormalities of the craniofacial complex, mental problems, subjects smoking or using other tobacco products, taking antibiotics during the last 2 months, use of chlorhexidine or another mouthwash in the last 3 weeks, allergy to cetylpyridinium chloride, and participating in other trials are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hydrogen sulfide (H2S), Methyl-mercaptan (CH3SH), Dimethyl sulfide ([(CH3)2S]) | — |
Countries
Japan
Contacts
Tsurumi University Department of Orthodontics, School of Dental Medicine