Intubated patient
Conditions
Interventions
1) Considering weaning from the ventilator, patients scheduled to undergo SBT will be fitted with intraesophageal pressure monitor and EIT for monitoring prior to SBT (Monitoring 1). 2) Patients in b
Sponsors
The University of Tokushima Hospital Department of Emergency and Intensive Care Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients 18 years of age or older who have been on ventilatory management in the ICU for at least 48 hours and are considered for weaning from the ventilator (SBT can be cleared).
Exclusion criteria
Exclusion criteria: Patients who cannot maintain airway patency (impaired consciousness, weak cough reflex, high airway secretions, positive cufflink test, etc.), severely obese (BMI>35 kg/m2), patients with chest trauma or other difficulties in EIT monitoring, post esophageal surgery, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| work of breathing (pressure time product with esophageal pressure), transpulmonary pressure (inspiratory transpulmonary pressure, delta transpulmonary pressure), oxygenation after extubation, end-expiratory lung volume (end-expiratory impedance), ventilation distribution (tidal impedance variation), and pendelluft phenomenon. | — |
Secondary
| Measure | Time frame |
|---|---|
| Successful weaning from ventilator Respiratory failure and reintubation rate at 72 hours after extubation Respiratory complications (pneumonia, hypoxemia, upper airway obstruction, bronchospasm, etc.) for 5 days after extubation or until ICU discharge | — |
Countries
Japan
Contacts
Public ContactTakuya Takashima
The University of Tokushima Hospital Department of Emergency and Intensive Care Medicine
Outcome results
None listed