The Effect of High-Flow Nasal Cannula Oxygen Therapy on Respiratory Muscle

The Effect of High-Flow Nasal Cannula Oxygen Therapy on Respiratory Muscle - The Effect of High-Flow Nasal Cannula Oxygen Therapy on Respiratory Muscle

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000055470

Enrollment

Registered

2024-09-11

Start date

2022-10-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients 18 years of age or older for whom HFNC is considered appropriate at the time of consent. Patients with acute respiratory failure (PaO2/FIO2&lt

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Acute respiratory failure (PaO2/FIO2<300, SpO2<92%, etc., requiring oxygenation) Post-extubation high risk (age > 65 years, chronic heart failure, APACHE II score > 12, BMI > 30, airway problems, difficult weaning, duration of ventilator management > 7 days, one or more of the following) and post thoracic surgery (ARISTAT score > 26 points, obesity, high risk of cardiac and pulmonary disease)

Exclusion criteria

Exclusion criteria: Highly obese (BMI>40), pregnant women, history of neuromuscular disease, cervical cord injury or post-surgical spinal cord injury, abdominal obstruction, post-tracheostomy, severe COPD, overactive delirium, agitation

Design outcomes

Primary

Measure	Time frame
The results of this study will evaluate the changes in DTei, DTee, ETei, ETee, DTF, ETF, DTF/respiratory rate, and ETF/respiratory rate before and after wearing HFNC as changes in respiratory effort. In addition, the relationship between inspiratory and expiratory muscles will be evaluated.	—

Countries

Japan

Contacts

Public ContactTakuya Takashima

Tokushima University Hospital Department of Emergency and Intensive Care Medicine

t.takashima0405@gmail.com0886313111

Outcome results