Exploratory Study of the Correlation between Intron Retention (IR) Variability and Depression Scores

Exploratory Study of the Correlation between Intron Retention (IR) Variability and Depression Scores - Exploratory Study of Intron Retention (IR) Variability and Depression Scores

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000055403

Enrollment

Registered

2024-09-03

Start date

2025-09-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive symptoms

Interventions

Taking the Kampo medicine (Kamikihito) for 2 months.

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: ?Subjects aged 18-65. ?Subjects whose Beck Depression Inventory - Second Edition score are less than 28 points.

Exclusion criteria

Exclusion criteria: ?Subjects undergoing depression treatment. ?Subjects who have taken Kampo medicines within the last 4 weeks. ?Subjects who have taken antibiotics within the last 4 weeks. ?Subjects who clearly need Western medical care. ?Subjects diagnosed with ulcerative colitis or Crohn's disease. ?Subjects with hepatic dysfunction or renal dysfunction. ?Subjects who participated in other clinical studies within 12 weeks before the start of study. ?Subjects judged by the attending physician to be ineligible.

Design outcomes

Primary

Measure	Time frame
Intron Retention (IR) associated with changes in depression scores	—

Countries

Japan

Contacts

Public ContactAkino Wakasugi

Kitasato University Kitasato Institute Hospital, Department of Research

omrc-ebm@insti.kitasato-u.ac.jp03-5791-6346

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026