Additional analysis to evaluate activity index of pustulotic arthro-osteitis <A Phase 3, Placebo-Controlled, Double-Blind Comparative Study of KHK4827 With an Open-Label Extension in Subjects With Palmoplantar Pustulosis>

Additional analysis to evaluate activity index of pustulotic arthro-osteitis <A Phase 3, Placebo-Controlled, Double-Blind Comparative Study of KHK4827 With an Open-Label Extension in Subjects With Palmoplantar Pustulosis> - Additional analysis of 4827-009 study on pustulotic arthro-osteitis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000055398

Enrollment

Registered

2024-09-03

Start date

2024-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pustulotic arthro-osteitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients participating in 4827-009 study who met criteria for pustulotic arthro-osteitis as defined by the study

Exclusion criteria

Exclusion criteria: Patients who participated in the trial but did not obtain either all the imaging indexes or all the non-imaging indexes.

Design outcomes

Primary

Measure	Time frame
Correlation analysis of MRI Chest Area of edema and major non-imaging indexes Correlation analysis of MRI Chest Intensity of edema and major non-imaging indexes Correlation analysis of MRI Sacroiliac joints (SPACC) and major non-imaging indexes Correlation analysis of MRI spine (SPARCC) and major non-imaging indexes	—

Secondary

Measure	Time frame
Correlation analysis of MRI Chest Area of edema and other non-imaging indexes Correlation analysis of MRI Chest Intensity of edema and other non-imaging indexes Correlation analysis of MRI Sacroiliac joints (SPACC) and other non-imaging indexes Correlation analysis of MRI spine (SPARCC) and other non-imaging indexes Correlation analysis of other imaging indexes and non-imaging indexes Correlation analysis of MRI Chest Area of edema and other imaging indexes Correlation analysis of MRI Chest Intensity of edema and other imaging indexes Correlation analysis of MRI Sacroiliac joints (SPACC) and other imaging indexes Correlation analysis of MRI spine (SPARCC) and other imaging indexes	—

Measure

Time frame

Correlation analysis of MRI Chest Area of edema and other non-imaging indexes Correlation analysis of MRI Chest Intensity of edema and other non-imaging indexes Correlation analysis of MRI Sacroiliac joints (SPACC) and other non-imaging indexes Correlation analysis of MRI spine (SPARCC) and other non-imaging indexes Correlation analysis of other imaging indexes and non-imaging indexes Correlation analysis of MRI Chest Area of edema and other imaging indexes Correlation analysis of MRI Chest Intensity of edema and other imaging indexes Correlation analysis of MRI Sacroiliac joints (SPACC) and other imaging indexes Correlation analysis of MRI spine (SPARCC) and other imaging indexes

—

Countries

Japan

Contacts

Public ContactAkiyo Nozaki

Kyowa Kirin Co., Ltd. Clinical Development Center

khk4827.ppp-clinical.st@kyowakirin.com03-5205-7200

Outcome results