Evaluation of intestinal mucosa in patients with inflammatory bowel disease

Evaluation of intestinal mucosa in patients with inflammatory bowel disease - Evaluation of intestinal mucosa in patients with inflammatory bowel disease

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000055385

Enrollment

200

Registered

2024-09-01

Start date

2020-08-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflamamatory bowel disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 Patients diagnosed with UC or CD and undergoing treatment at this hospital 2 Patients who have the capacity to consent and whose written consent can be obtained 3 Patients who are scheduled for surgical treatment or have already undergone surgical treatment 4 Patients with no history of UC or CD, diagnosed with colorectal cancer and scheduled for surgical treatment

Exclusion criteria

Exclusion criteria: 1 Patients who did not give consent for this study 2 Patients deemed by the treating physician to be ineligible for enrollment in this study

Design outcomes

Primary

Measure	Time frame
For patients diagnosed with IBD and undergoing treatment at the hospital, biopsies are performed during upper and lower endoscopy to evaluate the intestinal mucosa (preoperative evaluation). For patients who undergo surgery during the course of treatment, biopsies of normal and ulcerated areas and stool samples are obtained from intraoperative endoscopic and intraoperative specimens (intraoperative evaluation). In addition, upper and/or lower gastrointestinal endoscopy is performed 10-14 days, 1 month, and 3 months postoperatively to evaluate the images and biopsy inflammation of the mucosa (postoperative evaluation).	—

Measure

Time frame

For patients diagnosed with IBD and undergoing treatment at the hospital, biopsies are performed during upper and lower endoscopy to evaluate the intestinal mucosa (preoperative evaluation). For patients who undergo surgery during the course of treatment, biopsies of normal and ulcerated areas and stool samples are obtained from intraoperative endoscopic and intraoperative specimens (intraoperative evaluation). In addition, upper and/or lower gastrointestinal endoscopy is performed 10-14 days, 1 month, and 3 months postoperatively to evaluate the images and biopsy inflammation of the mucosa (postoperative evaluation).

—

Countries

Japan

Contacts

Public ContactRyo Seishima

Keio Univeristy School of Medicine Department of Surgery

r_seishima@ybb.ne.jp0333531211

Outcome results