Healthy subjects
Conditions
Interventions
Subjects receive a single dose of carotenoids + water. After the washout period (13 days or more), subjects receive a single dose of carotenoids + EPS (4mg). After the washout period (13 days or more)
Sponsors
Meiji Co., Ltd.
Meiji Holdings Co., Ltd., CPCC Company Limited, Chiyoda Paramedical Care Clinic
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Subjects giving written informed consent 2) Males aged 20 to 35 years old when consent acquisition 3) Subjects whose body mass index (BMI) is from 18.5 kg/m2 to 25.0 kg/m2
Exclusion criteria
Exclusion criteria: 1) Subjects who routinely use pharmaceuticals, quasi-drugs, dietary supplement, and consume food for specified health uses, supplements containing carotenoids more than two days per week 2) Subjects who have chronic diseases necessitating treatments and/or medications 3) Subjects who have abnormal lipid metabolism, glucose metabolism, liver function, or kidney function 4) Subjects who received digestive surgical procedures 5) habitual smokers 6) Subjects who participate in other clinical trials within the past month or have plans to participate in other clinical trials during this study period 7) Subjects who have food allergy 8) Subjects who is conscious of being prone to diarrhea from dairy products 9) Subjects who donate 200 mL of blood within a month, or 400 mL of blood within three month 10) Subjects who determine ineligible by the principal investigator or sub-investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma beta-carotene concentration | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma concentrations of other carotenoids and their metabolites. | — |
Countries
Japan
Contacts
Public ContactSatomi Ichikawa
Meiji Co., Ltd. R&D Division
Outcome results
None listed