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Development of Machine Learning Algorithms Using Intracranial Electroencephalography and Exploration of Biomarkers for Mood Variability

Development of Machine Learning Algorithms Using Intracranial Electroencephalography and Exploration of Biomarkers for Mood Variability - NeuroAI for Mood Decoding

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000055336
Enrollment
50
Registered
2024-10-01
Start date
2024-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatment-resistant epilepsy

Interventions

While recording intracranial EEG, patients are presented with images for a total of 6 minutes, followed by a few minutes to complete questionnaires before and after the presentation. This process is r

Sponsors

TOKYO WOMEN'S MEDICAL UNIVERSITY, ADACHI MEDICAL CENTER
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who are scheduled to have, or have already had, intracranial electrodes implanted with the purpose of identifying the distribution of epileptic foci for surgical treatment of refractory epilepsy, and who have consented to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Patients under 20 years old or over 66 years old. 2. Patients with severe intellectual disabilities who find it difficult to perform tasks. 3. Patients who are expected to have difficulty performing tasks or cooperating with the study due to complications or reduced physical strength following electrode placement surgery. 4. Other patients deemed unsuitable as study subjects by the principal investigator.

Design outcomes

Primary

MeasureTime frame
Accuracy of machine learning algorithms for predicting patient mood fluctuations

Secondary

MeasureTime frame
1. Identification of the machine learning algorithms, brain regions, frequency bands, and biomarkers that most contribute to predicting mood fluctuations in patients. 2. Verification of the differences found in item 1 across different subjects.

Countries

Japan

Contacts

Public ContactYuichi Kubota

TOKYO WOMEN'S MEDICAL UNIVERSITY, ADACHI MEDICAL CENTER Department of Neurosurgery

kubota.yuichi@twmu.ac.jp03-6807-1650

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026