Bipolar disorder patients and Healthy individuals without psychiatric disorders
Conditions
Interventions
Bipolar patients
Healthy volunteers
Sponsors
Saitama Medical University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria Those who meet all of the following criteria will be included in the study. [All subjects] Age: 20-90 years for FAST, 50-90 years for FASTO who are not employed. Gender does not matter. Subjects who have fully understood the purpose of the study and given written consent after receiving a written explanation approved in advance by Saitama Medical University Hospital IRB (hereafter referred to as the Hospital IRB), as well as a sufficient oral explanation. Restrictions on concomitant medications: None [Bipolar Disorder Patients] Patients who visited the Neuropsychiatry and Psychosomatic Medicine Department of Saitama Medical University Hospital and were invited to participate by the principal investigator or researcher, and patients who applied voluntarily after seeing a poster or other recruitment notice. Patients who meet the diagnostic criteria for bipolar disorder based on the Diagnostic and Statistical Manual of Mental Disorder, 5th Edition (DSM-5-TR) created by the American Psychiatric Association. Inpatient or outpatient care is not required. Diagnosis is made by clinical diagnostic interview and the Mini International Neuropsychiatric Interview (MINI). Screening is performed by clinical interview and structured interview MINI. Medication is not required. [Healthy Subjects] Patients who applied voluntarily after seeing a poster or other notice. Those who are not found to have a neurological or psychiatric disorder by clinical interview and MINI.
Exclusion criteria
Exclusion criteria: Those who meet any of the following criteria will be excluded from this study. [All subjects] Individuals with an IQ below 70 or an equivalent educational background (e.g., graduating from a special needs school). Individuals with low cognitive function (Mini Mental Statement Examination (MMSE) < 18). Other individuals who the researcher deems unsuitable as subjects, such as those with extremely unstable mental symptoms (e.g., those who have repeatedly attempted suicide). [Healthy subjects] Individuals diagnosed with a mental illness in the MINI. ndividuals with a first-degree blood relative with a mental illness. Individuals with a history of continuous use of antipsychotics or antidepressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The reliability of FAST (FASTO), SOFAS, and SDS will be compared between the first and second evaluation scores using correlation coefficients . The internal consistency (validity) of FAST (FASTO) will be evaluated by calculating Cronbach's alpha coefficient . | — |
Secondary
| Measure | Time frame |
|---|---|
| To verify correlation coefficients between functional impairment in bipolar patients, such as increases in FAST (FASTO), and the severity of clinical symptoms. | — |
Countries
Japan
Contacts
Public ContactHisatoshi Arai
Saitama Medical University Hospital Department of Psychiatry
Outcome results
None listed