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The Exploration of Neurological Foundations of Chronic Postoperative Pain

The Exploration of Neurological Foundations of Chronic Postoperative Pain - The Exploration of Neurological Foundations of Chronic Postoperative Pain

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000055267
Enrollment
300
Registered
2024-08-18
Start date
2024-08-20
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic postoperative pain

Interventions

None listed

Sponsors

Keio University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients classified as ASA-PS Class 1 or 2 according to the American Society of Anesthesiologists' Physical Status Classification System. Patients who provide written consent to participate in this study.

Exclusion criteria

Exclusion criteria: Patients who have any pain prior to surgery. Patients undergoing surgery for pneumothorax or pectus excavatum in the Department of Respiratory Surgery. Patients undergoing mastectomy with expander insertion. Other patients who cannot undergo MRI imaging (e.g., those with claustrophobia or magnetic metallic implants in their body). Patients currently involved in compensation claims related to pain (e.g., workers' compensation, welfare benefits) or ongoing litigation. Patients deemed unsuitable for this study by the principal investigator or co-investigators.

Design outcomes

Primary

MeasureTime frame
The average NRS at 1 month and at 3-6 months after surgery.

Secondary

MeasureTime frame
Resting NRS at 3-6 months after surgery. Movement-evoked NRS at 3-6 months after surgery. Resting NRS at 1 month after surgery. Movement-evoked NRS at 1 month after surgery. Relationship between postoperative pain intensity and brain function at 3-6 months after surgery. Relationship between postoperative pain intensity and brain function at 1 month after surgery. Exploration of factors leading to Chronic Post Surgical Pain based on patient background and perioperative information.

Countries

Japan

Contacts

Public ContactSaki Takaoka

Keio University School of Medicine Department of Anesthesiology

saki.takaoka@keio.jp03-5363-3810

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026