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The impact of cough receptor sensitivity and airway ciliary function on the onset and course of pulmonary nontuberculous mycobacteria.

The impact of cough receptor sensitivity and airway ciliary function on the onset and course of pulmonary nontuberculous mycobacteria. - The impact of cough receptor sensitivity and airway ciliary function on the onset and course of pulmonary nontuberculous mycobacteria.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000055192
Enrollment
300
Registered
2024-08-07
Start date
2024-08-07
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary nontuberculous mycobacteria

Interventions

None listed

Sponsors

Kanazawa University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) subjects with aged 20 years or older 2) subjects with suspected or diagnosed pulmonary nontuberculous mycobacteria Chest imaging findings are suspicious for pulmonary nontuberculous mycobacteria and are met by seeing one of the following a) culture positive on at least one sputum specimen b) culture positive on at least one bronchial lavage fluid c) Transbronchial lung biopsy specimen shows histological findings consistent with mycobacterium infections. d) positive for MAC antibodies 3) other pulmonary nontuberculous mycobacteria can be excluded 4) subjects who can get documentary consent by one's own free will after enough informed consent

Exclusion criteria

Exclusion criteria: 1) subjects with pregnant, lactating or possibly pregnant 2) subjects with bronchial asthma or eosinophilic chronic rhinosinusitis 3) subjects taking gefapixant 4) subjects with a history of bronchial thermoplasty 5) others who judged inappropriate by other research researcher or research sharing doctor

Design outcomes

Primary

MeasureTime frame
Capsaicin cough receptor sensitivity and airway ciliary beat frequency in patients with pulmonary nontuberculous mycobacteria.

Secondary

MeasureTime frame
Correlation between the capsaicin cough reflex sensitivity and the exacerbation of pulmonary nontuberculous mycobacteria. Correlation between the airway ciliary beat frequency and the exacerbation of pulmonary nontuberculous mycobacteria.

Countries

Japan

Contacts

Public ContactKenta Yamamura

Kanazawa University Hospital Respiratory medicine

kenta-yamamura@staff.kanazawa-u.ac.jp0762652000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026