All tumors requiring pancreatoduodenectomy including biliary tract cancer, pancreatic cancer, and duodenal cancer.
Conditions
Interventions
None listed
Sponsors
Shizuoka Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (I) Patients who are aged 20-79 years. (II) Patients who are able to provide written informed consent. (III) Patients who are considered reliable in expressing their symptoms according to a questionnaire. (IV) Patients who are scheduled to undergo PD. (V) Patients who had undergone preoperative chemotherapy or had a history of gastrectomy will be also included.
Exclusion criteria
Exclusion criteria: (I) Patients with psychiatric diseases including dementia. (II) Patients with liver cirrhosis. (III) Patients with renal failure (creatinine over 2 mg/dL). (IV) Patients with anemia (hemoglobin under 9.0 g/dL). (V) Patients who are scheduled to undergo hepato-pancreatoduodenectomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency and characteristics of perioperative dysgeusia during hospitalization for pancreatoduodenectomy (between 2 days before surgery and postoperative day 21). | — |
Secondary
| Measure | Time frame |
|---|---|
| The frequency and characteristics of dysgeusia before surgery and on postoperative day 3, 7, 14, and 21. Serum levels of trace metal elements before surgery and on postoperative day 1, 3, 7, 14, and 21 in the patients with and without perioperative dysgeusia. (Trace metal elements include iron, zinc, magnesium, copper, inorganic phosphate, and calcium). | — |
Countries
Japan
Contacts
Public ContactKatsuhisa Ohgi
Shizuoka Cancer Center Division of Hepato-Biliary-Pancreatic Surgery
Outcome results
None listed