Efficacy test of the oral components

Ingestion test of the oral components T0212_2024 - Efficacy test of the oral components

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000055130

Enrollment

Registered

2024-08-01

Start date

2024-08-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Ingest oral components T0212 3 times a day for 8 weeks Ingest placebo 3 times a day for 8 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Human aged 20-59 2. Person agrees to use the designated toothpaste and toothbrush and to consume the test product during the study period (Interdental brushes and dental floss may be used, mouthwash or liquid toothpaste other than the designated dentifrice may not be used)

Exclusion criteria

Exclusion criteria: 1. Person who are hypersensitive to drugs such as allergies 2. Person who have five major diseases (cancer, stroke, acute myocardial infarction, diabetes, mental illness), etc. and are being treated at a medical institution, or who are scheduled for surgery, etc. 3. Pregnant women, those who may be pregnant, or those who are breastfeeding 4. Person who have taken antibiotics within three month 5. Person who are currently participating in clinical trials related to other oral cavities and food ingestion 6. Person who have had teeth extraction other than wisdom teeth performed or dental surgery within the past 3 months 7. Person who are currently visiting a dental clinic and receiving oral treatment 8. Person who have more than 5 missing teeth (excluding wisdom tooth extraction and extraction due to orthodontics) 9. Person who have obvious trauma in the oral cavity 10. Person who have severe gingival inflammation 11. Person who have a habit of smoking at least one cigarette per day 12. Other persons who are judged by the dentist in charge of the test or the person in charge of the study to be inappropriate as a participant in the study

Design outcomes

Primary

Measure	Time frame
Amount of plaque	—

Secondary

Measure	Time frame
Halitosis Bacterial ratios in saliva, dental plaque, and tongue coating Questionnaire Gingival inflammation	—

Countries

Japan

Contacts

Public ContactRina Tsurumi

Kao Corporation Human Healthcare Research Lab.

tsurumi.rina2@kao.com+81-3-5630-9747

Outcome results