Periodontal disease
Conditions
Interventions
Intervention 1: Toothpaste A (test toothpaste) =>
(washout period: 1 month) =>
Toothpaste B (placebo toothpaste) Test toothpaste: Toothpaste containing 0.05 w/w% isopropyl methylphenol, 0.1 w/w% tocopherol acetate, and 0.0347 w/v% propolis extract in toothpaste. Placebo toothp
Toothpaste A (test toothpaste) Test toothpaste: Toothpaste containing 0.05 w/w% isopropyl methylphenol, 0.1 w/w% tocopherol acetate, and 0.0347 w/v% propolis extract in toothpaste. Placebo toothpast
Sponsors
Meikai University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adults (students) with gingivitis or periodontitis
Exclusion criteria
Exclusion criteria: 1. Participants deemed unsuitable for the study by the dentist on the basis of an oral examination at the start of the study due to severe oral disease, perioral injury, etc. 2. Participants who have taken or are taking any medication (e.g. antibiotics) between one month before the start of the study and the end of the study that may affect the results of the study. 3. Participants who have prostheses, defects, etc. on the tooth being studied or its replacement that make them unsuitable for evaluation. 4. Any other participant whom the dentist considers unsuitable for any reasonable reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the efficacy of toothbrushing with propolis-containing toothpaste gel on the gingival index and plaque index after one and two weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the efficacy of toothbrushing with propolis-containing toothpaste gel on the bacterial flora in the tongue after one and two weeks. | — |
Countries
Japan
Contacts
Public ContactShigeru Amano
Meikai University School of Dentistry Meikai University Research Institute of Odontology
Outcome results
None listed