Defect closure after gastric endoscopic submucosal dissection using the reopenable-clip over the line method (ROLM) with or without self-assembled peptide solution : a randomized controlled trial

Defect closure after gastric endoscopic submucosal dissection using the reopenable-clip over the line method (ROLM) and self-assembled peptide solution : a randomised controlled trial. - Defect closure after gastric ESD using the ROLM and self-assembled peptide solution : A randomised controlled trial.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000055076

Enrollment

Registered

2024-07-26

Start date

2024-07-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric tumor

Interventions

ROLM and self-assembled peptide solution for closure group Reopenable-clip over the line method (ROLM) only closure group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Gastric ESD defects with a short diameter of 40 mm or less after gastric ESD

Exclusion criteria

Exclusion criteria: (1) Defects bordering the cardia or pylorus (2) Defects that extend more than a half circumference of the stomach. (3)Patients who have been judged as inappropriate for this study

Design outcomes

Primary

Measure	Time frame
Defect closure rate after ESD, defect closure rate at 2 weeks	—

Secondary

Measure	Time frame
Post-ESD adverse events (postoperative bleeding rate, postoperative perforation rate), defect closure time, number of clips, device cost, Number of times hemostatic forceps were used during closure	—

Countries

Japan

Contacts

Public ContactTatsuma Nomura

Suzuka General Hospital Gastroenterology

m06076tn@icloud.com0593821311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026