Dominantly inherited Alzheimer's network (DIAN) Japan Study

Dominantly inherited Alzheimer's network (DIAN) Japan Study - DIAN-Japan Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000055066

Enrollment

Registered

2024-08-01

Start date

2024-02-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer&#39

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Written informed consent obtained from participant and collateral source prior to any study-related procedures. Aged 18 (inclusive) or older and the child of an affected individual (clinically or by testing) in a pedigree with a known mutation for ADAD. Cognitively normal to very mild or mild cognitive impairment (CDR score range 0-1.0). Has study partner who are not their full-blooded siblings who can serve as collateral sources for the study. Fluent in a language at about the 6th grade level or above.

Exclusion criteria

Exclusion criteria: Under age 18 Medical or psychiatric illness that would interfere in completing initial and follow-up visits Requires nursing home level care Has no one who can serve as a study informant

Design outcomes

Primary

Measure	Time frame
Clinical Dementia Rating (CDR)	—

Secondary

Measure	Time frame
CSF and blood biomarkers, PET, MRI, cognitive tests	—

Countries

Japan

Contacts

Public ContactTakeshi Ikeuchi

Niigata University Brain Research Institute

dian-j@bri.niigata-u.ac.jp025-227-2344

Outcome results