Chronic rhinosinusitis with nasal polyps
Conditions
Interventions
In drug spraying using a flexible endoscope through a treatment channel group, the doctor inserts the flexible endoscope with a treatment channel into the sinus cavity to be treated, confirms the trea
s treatment channel, and sprays the drug with a syringe attached to the spraying catheter.
In drug spraying using a rigid endoscope through an otorhinolaryngologic catheter group, the doctor inserts t
Sponsors
Dokkyo Medical University
KEIHOKAI, Medical Corporation, MATSUWAKI CLINIC Shinagawa OLYMPUS MEDICAL SYSTEMS CORPORATION
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients over 18 years of age. Patients diagnosed with chronic rhinosinusitis with nasal polyp. Patients with a history of endoscopic sinus surgery and postoperative recurrence despite saline lavage of the sinuses and continuous nasal steroid spray treatment. Patients who have received a thorough explanation of their participation in this study and have given written consent of their own free will based on a thorough understanding.
Exclusion criteria
Exclusion criteria: Patients with allergy or intolerance to steroids. Patients with comorbid conditions require chemotherapy, immunotherapy, or oral steroids. Patients with clinical evidence of acute bacterial sinusitis, invasive fungal sinusitis, or diabetes mellitus. Patients with a history or diagnosis of glaucoma, ocular hypertension, or cataracts. Other patients were deemed inappropriate by the physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in edematous lesions of the sinonasal mucosa according to endoscopic findings before the treatment and one month after the treatment in the spraying of steroids through an otolaryngological catheter under the observation of a rigid endoscope or through a scope channel using a flexible endoscope. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in CT findings before and one month after treatment Availability of steroid sprays and difficulty of accessing the spray catheter to the treatment area Changes in scores and percentages on the symptom questionnaire and the patient tolerance questionnaire | — |
Countries
Japan
Contacts
Public ContactTsuguhisa Nakayama
Dokkyo Medical University Hospital Otorhinolaryngology and Head & Neck Surgery
Outcome results
None listed