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Study on Diagnostic Value of Microparticles in Exhaled Breath

Multicenter prospective observational study assessing diagnostic value of microparticles involved in human exhaled breath - MICROBREATH study

Status
Active, not recruiting
Phases
Phase 2
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000054979
Enrollment
600
Registered
2024-07-18
Start date
2024-07-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with various pulmonary diseases with definitive diagnosis using bronchoscopy

Interventions

None listed

Sponsors

Nagoya university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adults aged 20 years or older who underwent respiratory endoscopy at the study center for the diagnosis of various lung diseases, including lung cancer, diffuse lung disease, chronic obstructive lung disease, asthma, and lung infection. A control group of healthy subjects who understand the purpose of the study will also be selected.

Exclusion criteria

Exclusion criteria: Cases in which breath collection is difficult due to the following conditions: Poor general condition, including consciousness, circulation, and respiration. Lack of cooperation in breath collection. Presence of dyspnea, unable to endure breath collection through the circuit for more than 5 minutes. Postoperative deformities of the face and oral cavity, or conditions such as tracheostomy, making breath collection through a mouthpiece impossible. Any other conditions deemed inappropriate for breath collection by the attending physician.

Design outcomes

Primary

MeasureTime frame
Prediction accuracy of lung disease diagnosis by nano-particle analysis of exhaled breath condensate.

Countries

Japan

Contacts

Public ContactTomonori Sato

Nagoya university Department of Respiratory Medicine

satotomo.1005.90@gmail.com052-744-2167

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026