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Subjective and objective evaluation of salivary secretion in oral surgery under general anesthesia.

Investigate the effects of anesthetics on salivary function - Relationship between anesthetics and salivary function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000054973
Enrollment
30
Registered
2024-07-16
Start date
2024-07-16
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients over 20 years old who will undergo oral surgery under general anesthesia at Kanagawa Dental University Hospital.

Interventions

Anesthetic agents used in induction and maintenance of anesthesia in general anesthesia = Remimazolam Anesthetic agents used in induction and maintenance of anesthesia in general anesthesia = Propofol

Sponsors

Kanagawa Dental University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients over 20 years old who will undergo oral surgery under general anesthesia at Kanagawa Dental University Hospital

Exclusion criteria

Exclusion criteria: 1. people with an ASA-PS of 3 or higher 2. patients who are aware of thirst or are taking drugs that cause thirst 3. patients who have the following on blood drawn prior to the preoperative visit AST (GOT) or ALT (GPT) greater than 100 IU/L Serum creatinine > 2.0 mg/dL HbA1c greater than or equal to 7.5 4. taking benzodiazepines for more than 6 months 5. whose EEG and BIS values may not be properly measured (including vascular lesions) 6. who have a cardiac pacemaker or ICD 7. who have expressed (including verbally) their refusal to participate in this study 8. other subjects deemed inappropriate by the principal investigator

Design outcomes

Primary

MeasureTime frame
Subjective evaluation (salivation and discomfort) using Visual analogue scale from oral surgeon during pharyngeal pack insertion

Secondary

MeasureTime frame
1. amount of saliva aspiration during tracheal intubation 2. subjective evaluation (salivation and stress) by dental anesthesiologist using Visual Analogue Scale during tracheal intubation

Countries

Japan

Contacts

Public ContactShota Tsukimoto

Kanagawa dental university Department of dental anesthesiology

tsukimoto@kdu.ac.jp046-822-8810

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026