Skip to content

Effects of Anesthetic Drugs and Head Position Changes on Cerebral Tissue Oxygen Saturation in General Anesthesia.

How Cerebral Tissue Oxygen Saturation is Altered by Retroflexion and Head Rotation in General Anesthesia. - Effects of head retroflexion and head rotation on cerebral tissue oxygen saturation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000054972
Enrollment
20
Registered
2024-07-16
Start date
2024-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Men and women over 20 years old scheduled for oral surgery under general anesthesia at Kanagawa Dental University Hospital.

Interventions

Use of inhaled anesthetic agents in the maintenance of general anesthesia. Use of Propofol in the maintenance of general anesthesia. Use of Remimazolam in the maintenance of general anesthesia.

Sponsors

Kanagawa Dental University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Men and women over 20 years old scheduled for oral surgery under general anesthesia at Kanagawa Dental University Hospital.

Exclusion criteria

Exclusion criteria: 1. an ASA-PS of 3 or higher 2. blood samples taken prior to the preoperative visit that meet the following criteria AST (GOT) or ALT (GPT) greater than 100 IU/L Serum creatinine > 2.0 mg/dL HbA1c greater than or equal to 7.5 3. taking benzodiazepines for more than 1 year 4. whose EEG and BIS values may not be properly measured (including vascular lesions) 5. those with a cardiac pacemaker or ICD 6. who have expressed (including verbally) their refusal to participate in this study 7. other subjects deemed inappropriate by the principal investigator

Design outcomes

Primary

MeasureTime frame
The rate of change in Tissue Oxygen Index. In situations where near-infrared spectroscopy is used on brain tissue, tissue oxygen index and brain tissue oxygen saturation are synonymous.

Countries

Japan

Contacts

Public ContactShota Tsukimoto

Kanagawa dental university Department of dental anesthesiology

tsukimoto@kdu.ac.jp046-822-8810

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026